Skin cancer in immunosuppressed transplant patients: Vigilance matters
نویسندگان
چکیده
منابع مشابه
Immunosuppressants and skin cancer in transplant patients: focus on rapamycin.
BACKGROUND The responsibility of immunosuppressants for the increased risk of skin cancers in organ transplant recipients is widely recognized. Discerning the role of each drug is complicated owing to the fact that most patients generally have combinations of several medications. OBJECTIVE This article will discuss the role of the main immunosuppressants in the pathogenesis of skin cancers. ...
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Several advances in the filed of organ transplantation in last decades have resulted in significant increase in the number and methods of transplantation. In this article various aspects of organ transplantation including immunosuppressive medications, common skin tumors seen in transplant recipients, possible mechanisms involved in increased incidence of skin tumors and finally preventive meas...
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Squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) are the most frequent skin cancers in humans. An intact immune system is critical for protection against SCC since organ transplant recipients (OTR) have a 60- to 100-fold higher risk for developing these tumors. The role of the innate immune system in tumor immunosurveillance is unclear. Our aim was to determine the expression of sel...
متن کاملSkin cancer in organ transplant recipients.
Organ transplant recipients (OTR) are at a significantly increased risk for developing a wide variety of skin cancers, particularly epithelial skin cancer, Merkel cell carcinoma and Kaposi's sarcoma. Melanoma, skin adnexal neoplasm and cutaneous lymphomas are also more common in OTR and may differ in their clinicopathologic presentation from tumors in immunocompetent patients. The accuracy of c...
متن کاملNon-malignant skin changes in transplant patients.
The skin pathology seen in graft recipients is unique because they are usually seen in patients who have a long history of renal disease, where the characteristic lesions seen in pre-terminal failure followed by dialysis-induced skin pathology had developed. The skin changes after renal transplantation partially replace, and partially are superimposed upon, the skin lesions characteristic for t...
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ژورنال
عنوان ژورنال: World Journal of Hepatology
سال: 2015
ISSN: 1948-5182
DOI: 10.4254/wjh.v7.i4.717